| 许国华,叶晓健,袁文,肖建如,史建刚,田纪伟,陈德玉,倪斌,贾连顺,李家顺.经皮穿刺椎体成形术治疗胸腰椎转移性肿瘤[J].脊柱外科杂志,2006,4(1):17-20. |
经皮穿刺椎体成形术治疗胸腰椎转移性肿瘤  点此下载全文 (Fulltext) |
| 许国华 叶晓健 袁文 肖建如 史建刚 田纪伟 陈德玉 倪斌 贾连顺 李家顺 |
| 200003 上海, 第二军医大学附属长征医院骨科;200003 上海, 第二军医大学附属长征医院骨科;200003 上海, 第二军医大学附属长征医院骨科;200003 上海, 第二军医大学附属长征医院骨科;200003 上海, 第二军医大学附属长征医院骨科;200003 上海, 第二军医大学附属长征医院骨科;200003 上海, 第二军医大学附属长征医院骨科;200003 上海, 第二军医大学附属长征医院骨科;200003 上海, 第二军医大学附属长征医院骨科;200003 上海, 第二军医大学附属长征医院骨科 |
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| DOI： |
| 摘要点击次数: 1008 |
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| 摘要： |
| 目的 研究经皮穿刺椎弓根途径椎体成形术对胸、腰椎椎体转移性肿瘤的临床效果及其机理。方法 对31例46个胸、腰椎椎体转移癌患者施行经皮椎弓根途径骨水泥注入，对患者疼痛程度采用视觉模拟评分法进行治疗前后评估、分级，术前术后神经功能评定，分别对患者术后1周、3个月、6个月、12个月进行疼痛、神经症状和生活质量进行评价。结果 31例患者18例局麻药药效消失后疼痛缓解，8例48 h疼痛缓解，2例1周疼痛缓解，1例4周后疼痛缓解，但有2例术后出现神经症状加重。11例出现骨水泥渗漏，其中2例术后出现神经根损伤，1例出现马尾神经综合征，1例出现肺部小栓塞灶。结论 经皮穿刺椎弓根途径椎体成形术对胸、腰椎转移性肿瘤具有良好的止痛效果，能够有效预防椎体病理性骨折的发生，改善患者的生活质量。 |
| 关键词：胸椎 腰椎 脊椎肿瘤 肿瘤转移 甲基丙烯酸甲酯类 经皮穿刺椎体成形术 |
| Percutaneous vertebroplasty for the treatment of thoracolumbar metastatic tumors Fulltext |
| XU Guohua YE Xiaojian YUAN Wen |
| Department of Orthopaedics, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China;Department of Orthopaedics, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China;Department of Orthopaedics, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China;Department of Orthopaedics, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China;Department of Orthopaedics, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China;Department of Orthopaedics, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China;Department of Orthopaedics, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China;Department of Orthopaedics, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China;Department of Orthopaedics, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China;Department of Orthopaedics, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China |
| Fund Project: |
| Abstract: |
| Objective To study the result and mechanism of percutaneous vertebroplasty (PVP) via pedicle of vertebra in treating thoracolumbar metastatic tumors. Methods Thirty-one patients of thoracolumbar metastatic tumors involved 46 vertebral bodies were treated with percutaneous injections of cement (Polymethyl methacrylate PMMA) via pedicle of vertebra under X-ray guidance. The degree of pain was evaluated and classified by visual-analogue scale (VAS). All of the patients were examined at one week, and three, six and twelve months after surgery to evaluate the improvement of the pain, neurological symptom and living quality. Results The pain was relieved in 18 cases after the effect of local anesthetic disappeared, 8 cases 48 hours after operation, 2 cases 2 weeks after operation and 1 case 4 weeks after operation. But neurological symptom was aggravated in 2 cases after operation. Eleven cases had the leakage of cement, including 2 cases with nerve root injury, 1 case with neural syndrome of cauda equina and 1 case with microembolism in the lung. Conclusion Percutaneous vertebroplasty (PVP) via pedicle of vertebra has satisfactory antalgic effect on thoracolumbar metastatic tumors and can effectively prevent pathologic fracture of vertebral body to improve quality of patient's life. |
| Keywords:cervical vertebrae lumbar vertebrae spinal neoplasms neoplasm metastasis methylmethacrylates percutaneous vertebroplasty |
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