| 地里下提,古甫丁,马良.结核感染T细胞斑点试验在脊柱结核诊断中的应用[J].脊柱外科杂志,2014,12(6):357-359. |
结核感染T细胞斑点试验在脊柱结核诊断中的应用  点此下载全文 (Fulltext) |
| 地里下提 古甫丁 马良 |
| 830049 新疆维吾尔自治区, 新疆维吾尔自治区胸科医院骨科;830049 新疆维吾尔自治区, 新疆维吾尔自治区胸科医院骨科;830049 新疆维吾尔自治区, 新疆维吾尔自治区胸科医院骨科 |
| 基金项目： |
| DOI：10.3969/j.issn.1672-2957.2014.06.009 |
| 摘要点击次数: 921 |
| 全文下载次数: 673 |
| 摘要： |
| 目的 探讨结核感染T细胞斑点试验在脊柱结核诊断中的临床应用价值。方法 选取2012年4月～2013年1月本院骨科病区收治的疑似脊柱结核患者156例,分别采用结核感染T细胞斑点试验和结核菌素试验进行诊断,比较两者对脊柱结核诊断的临床意义(包括灵敏性、特异性、假阳性率和假阴性率指标的差别)。结果 结核感染T细胞斑点试验的灵敏性和特异性明显高于结核菌素试验(P<0.05);同时,结核感染T细胞斑点试验的假阳性率和假阴性率明显低于结核菌素试验试验(P<0.05)。结论 结核感染T细胞斑点试验在诊断脊柱结核中具有良好的敏感性和特异性,具有重要临床应用价值。 |
| 关键词：结核,脊柱 结核菌素试验 T淋巴细胞 敏感性与特异性 |
| Primary study of T-cell spot of tuberculosis test in diagnosis of spinal tuberculosis Fulltext |
| DI Li-xia-ti GU Fu-ding MA Liang |
| Department of Orthopaedics, Chest Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830049, Xinjiang Uygur Autonomous Region, China;Department of Orthopaedics, Chest Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830049, Xinjiang Uygur Autonomous Region, China;Department of Orthopaedics, Chest Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830049, Xinjiang Uygur Autonomous Region, China |
| Fund Project: |
| Abstract: |
| Objective To investigate the diagnostic value of T-cell spot of tuberculosis(T-SPOT.TB) test in patients with spinal tuberculosis.Methods The recorded clinical data of 156 suspected patients with spinal tuberculosis during April 2012 to January 2013,were collected retrospectively and reviewed systematically by the T-SPOT.TB test and tuberculin skin test(TST). The sensitivity, specificity, false positive rate and false negative rate of 2 tests were compared.Results The sensitivity and specificity of T-SPOT.TB test was significantly higher than those of TST test(P<0.05);the false positive rate and false negative rate of T-SPOT.TB test were significantly lower than those of TST test(P<0.05).Conclusion T-SPOT.TB assay possesses satisfactory sensitivity and specificity in diagnosis of spinal tuberculosis, and it is an effective way for the diagnosis of spinal tuberculosis. |
| Keywords:Tuberculosis, spinal Tuberculin Test T-Lymphocytes Sensitivity and specificity |
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