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许耀,陈文钧.脊髓型颈椎病患者脊髓MRI T2加权像高信号改变和维生素B12水平的关系[J].脊柱外科杂志,2018,16(3):163-166.
脊髓型颈椎病患者脊髓MRI T2加权像高信号改变和维生素B12水平的关系     点此下载全文 (Fulltext)
许耀  陈文钧
复旦大学附属华山医院骨科, 上海 200040
基金项目:
DOI:10.3969/j.issn.1672-2957.2018.03.008
摘要点击次数: 62
全文下载次数: 45
摘要:
      目的 探讨脊髓型颈椎病(CSM)患者脊髓MRI T2加权像(MRI T2WI)高信号改变与血清维生素B12水平之间的关系。方法 2007年6月-2010年6月,本院共收治确诊CSM患者91例,按照脊髓MRI T2WI有无高信号改变对患者进行分组,有高信号改变为研究组(47例),无高信号改变为对照组(44例)。对患者的血清维生素B12水平进行检测,并分析维生素B12水平与MRI T2WI高信号、性别、年龄、脊髓受压程度之间的关系。结果 有高信号改变患者血清维生素B12水平明显降低,与无高信号改变患者相比差异具有统计学意义(P<0.05)。高信号改变和维生素B12水平下降具有相关性。结论 脊髓MRI T2WI高信号改变和血清维生素B12水平存在相关性,血清维生素B12水平可能与CSM的发生相关。
关键词:颈椎  颈椎病  磁共振成像  维生素B12
Relationship between increased signal intensity on MRI T2 weighted image and vitamin B12 level in cervical spondylotic myelopathy    Fulltext
XU Yao  CHEN Wen-jun
Department of Orthopaedics, Huashan Hospital, Fudan University, Shanghai 200040, China
Fund Project:
Abstract:
      Objective To investigate the relationship between the increased signal intensity on MRI T2 weighted image (MRI T2WI) and serum vitamin B12 level in cervical spondylotic myelopathy(CSM). Methods From June 2007 to June 2010, there were 91 patients diagnosed as having CSM. The patients were divided into 2 groups according to the signal intensity on MRI T2WI, patients with high signal serving study group(47 cases), those without high signal as control group(44 cases). Serum vitamin B12 levels were detected in these patients. The relationship between the vitamin B12 level and the increased signal intensity on MRI T2WI, gender, age and spinal cord compression degree were analyzed. Results The serum vitamin B12 levels in patients with high signal change were significantly lower than those without high signal changes and the difference was statistically significant(P<0.05). Statistically significant linear relationship was demonstrated between Vitamin B12 and the increased signal intensity. Conclusion The increased signal intensity on MRI T2WI is related to serum vitamin B12, and the latter may be a prognostic factor for patients with CSM.
Keywords:Cervical vertebrae  Cervical spondylosis  Magnetic resonance imaging  Vitamin B12
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