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徐增,吴卉乔,孙斌,张科,石长贵,谢玮,张颖,吴晓东,陈华江,袁文.可吸收止血流体明胶在钩椎关节切除术中的应用[J].脊柱外科杂志,2020,18(4):232-236.
可吸收止血流体明胶在钩椎关节切除术中的应用     点此下载全文 (Fulltext)
徐增1△  吴卉乔1△  孙斌1  张科1  石长贵1  谢玮2  张颖1  吴晓东1  陈华江1  袁文1*
1. 海军军医大学附属长征医院骨科, 上海 200003;
2. 方塔中医医院骨科, 上海 201600
基金项目:上海市自然科学基金(19ZR1456700)
DOI:10.3969/j.issn.1672-2957.2020.04.004
摘要点击次数: 492
全文下载次数: 206
摘要:
      目的 探讨可吸收止血流体明胶(SurgifloTM)应用于钩椎关节切除术中的有效性和安全性。方法 2017年1月—2019年5月海军军医大学附属长征医院采用钩椎关节切除术治疗神经根型颈椎病患者126例,术中使用可吸收止血流体明胶止血61例(Surgiflo组),采用明胶海绵止血65例(明胶海绵组)。记录2组术中止血时间、术中出血量、术后1 d和2 d引流量、术后1 d和末次随访日本骨科学会(JOA)评分,以及术后有无过敏、感染等并发症,综合评价2组治疗效果。结果 Surgiflo组术中止血时间、术中出血量、术后1 d和2 d引流量、术后1 d JOA评分均优于明胶海绵组,差异有统计学意义(P<0.05);2组末次随访JOA评分差异无统计学意义(P>0.05)。Surgiflo组和明胶海绵组术后伤口感染发生率分别为0和1.5%(1/65)。结论 可吸收止血流体明胶是一种安全、有效的止血剂,在钩椎关节切除手术中可减少术中止血时间、术中出血量、术后引流量,且围手术期症状缓解迅速,不增加伤口感染的风险。
关键词:颈椎病  截骨术  出血,手术
Application of thrombin-gelatin hemostatic matrix in uncovertebral joint decompression    Fulltext
XU Zeng1△  WU Hui-qiao1△  SUN Bin1  ZHANG Ke1  SHI Chang-gui1  XIE Wei2  ZHANG Ying1  WU Xiao-dong1  CHEN Hua-jiang1  YUAN Wen1*
1. Department of Orthpaedics, Changzheng Hospital, Navy Medical University, Shanghai 200003, China;
2. Department of Orthpaedics, Fangta Hospital of Traditional Chinese Medicine, Shanghai 201600, China
Fund Project:
Abstract:
      Objective To investigate the efficacy and safety of thrombin-gelatin hemostatic matrix(SurgifloTM) during uncovertebral joint decompression for treating cervical spondylosis. Methods From January 2017 to May 2019,126 cervical spondylotic radiculopathy patients were treated by uncovertebral joint decompression in Changzheng Hospital affiliated to Navy Medical University. Sixty-one cases were stopped of bleeding with thrombin-gelatin hemostatic matrix(Surgiflo group) and 65 with gelatin sponge(gelatin sponge group). The therapeutic effect of the 2 groups was evaluated by comparing the hemostasis time,intraoperative blood loss,drainage volume at postoperative 1 d and 2 d,Japanese Orthopaedic Association(JOA) score at postoperative 1 d and the final follow-up,and the postoperative complications such as allergy and infection. Results The hemostasis time,intraoperative blood loss,drainage volume at postoperative 1 d and 2 d,JOA score at postoperative 1 d of Surgiflo group were better than those of gelatin sponge group(P<0.05);there was no significant difference in JOA score at the final follow-up between the 2 groups(P>0.05). The incidence of postoperative infection was 0 and 1.5%(1/65) in Surgiflo group and gelatin sponge group,respectively. Conclusion Thrombin-gelatin hemostatic matrix is a safe and effective hemostatic agent,can reduce the hemostasis time,intraoperative blood loss and postoperative drainage in uncovertebral joint decompression,relieve the perioperative symptoms rapidly,and do not increase the risk of wound infection.
Keywords:Cervical spondylosis  Osteotomy  Blood loss,surgical
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